Leucocyte- and platelet-rich fibrin (L-PRF), a second-generation platelet concentrate and completely different from PRP. L-PRF is an autologous blood-derived product, which can be obtained, quickly and in a cost-effective manner. It is produced from peripheral blood, which is immediately centrifuged without any anticoagulant. L-PRF is rich in fibrin, platelets (± 90% of initial blood) and leucocytes (± 70% of initial blood), and can be transformed into strong membranes of about 1 mm in thickness. L-PRF membranes release large amounts of growth factors for a long period (up to 7 days) and they possess an antibacterial capacity. As such L-PRF membranes offer “significant” and “clinically relevant” advantages in several indications including: ridge preservation, sinus augmentation, horizontal/vertical bone augmentation and osseointegration.

Learning objectives
After this presentation delegates will understand the:

  • Basic steps in the preparation of L-PRF
  • Biological background of L-PRF
  • Clinical benefits of L-PRF in dento-alveolar surgery